1119 lines
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1119 lines
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<title>The gradual evolution of embryological development</title>
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<meta name="author" content="Amr Gharbeia">
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<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><font color="#993366"><font face="Verdana, sans-serif"><b>T<img src="data:image/png;base64,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" name="TtsOtkCRS04_11" align="right" width="275" height="46" border="0">he
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gradual evolution of embryological development. </b></font></font>The
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evolution of the mechanism of embryological development is
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responsible for the most spectacular punctuation in the whole course
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of evolution, the Cambrian revolution at the very beginning of the
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fossil record some 600 million years ago, when many different species
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of multicellular animals suddenly showed up. Only when animals
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evolved hard parts, like shells, did fossils form, and the same
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mechanism that constructs such hard parts also constructs the nervous
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system.</font></font></font></p>
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<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">Tracing
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the actual evolution of the mechanism of embryological development on
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earth should settle any doubts that may remain about the
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inevitability of the evolution of multicellular animals, because it
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shows concretely how such a mechanism lies within the range of
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variations on animal-like protists. </font></font></font>
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</p>
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<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">This
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rather technical history, however, serves an additional function in
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this ontological argument, because it leads to an explanation of the
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difference between proterostomes and deuterostomes (that is, between
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most invertebrate development and development in chordates, such as
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vertebrates and mammals). That will account for the radical
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difference between two groups of telesensory animals (invertebrates
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and vertebrates), and the nature of the difference between them will
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explain why proterostomes do not evolve to the third and fourth
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animal stages of evolution.</font></font></font></p>
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<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><font face="Verdana, sans-serif">T<img src="data:image/png;base64,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" name="TtsOtkCRS04_12" align="right" width="250" height="23" border="0">he
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origin of the mechanism of embryological development.</font> Clues
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about the evolution of animals can be found by comparing how the
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various kinds of animals develop. The first steps in embryological
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development are least likely to have changed during evolution, for
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whatever the mechanism, variations in it would probably throw the
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whole process off track. Evolution occurs mostly by adding new
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structures to the process. And we can see how animals with nervous
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system began by identifying the first form of development. Let us
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compare the three basic forms of development. </font></font></font>
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</p>
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<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><i><b>Gastrulation.</b></i>
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More complex animals, both proterostomes and deuterostomes, develop
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by a process of gastrulation. The fertilized egg cell is an unusually
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large cell, and asexual division produces many daughter cells
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(cleavage). They secrete a fluid in their midst and arrange
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themselves in a layer, enclosing it like the surface of a sphere.
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They are the blastula, and the cell-free area in their midst is the
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blastocoel. </font></font></font>
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</p>
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<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; text-indent: -3.18cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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" name="Gastrulation" align="bottom" width="750" height="275" border="0"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><span lang="en-US">Gastrulation
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follows the formation of the blastula. Its function is to establish a
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second layer of cells beneath the first. The cells destined to become
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the second layer, or endoderm, are one hemisphere of the blastula.
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With more energy-rich yolk from the cytoplasm of the egg, they are
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larger than the cells in the other hemisphere, which becomes the
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ectoderm. The second layer forms by a folding inward (invagination)
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that never breaks the surface of the sphere: At about the margin
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between the two hemispheres, cells on the surface of the blastula
|
|
bend inward and start moving into the blastocoel, aligning themselves
|
|
along the underside of the sphere's surface. Ultimately, about half
|
|
the surface of the original sphere turns itself inside out to form
|
|
the second layer of cells on the underside of the other half of the
|
|
original sphere. But the resulting two-layered surface is not a
|
|
hemisphere: The missing hemisphere shrinks to the size of a hole in
|
|
the surface of a new, yet incomplete sphere. The hole, through which
|
|
the endoderm has disappeared, is the blastopore, and the inner
|
|
chamber, now lined with endoderm, is the archenteron. Finally, a
|
|
second opening is made through the two layers of cells, forming a
|
|
digestive tract between it and the blastopore. Differences that begin
|
|
at the this point distinguish proterostomes from deuterostomes.</span></font></font><sup><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><span lang="en-US"><a class="sdendnoteanc" name="sdendnote1anc" href="#sdendnote1sym"><sup>i</sup></a></span></font></font></sup><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><span lang="en-US">
|
|
(See diagram of Development in gastrulating animal.)</span></font></font></font></p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><i><b>Planuloid
|
|
development.</b></i> Animals with nervous system could not have begun
|
|
with gastrulation. The process involves such a complex coordination
|
|
of the behaviors of so many different cells that it could not
|
|
possibly have been the first step by which protists organized
|
|
themselves multicellularly. Development occurs in another way in two
|
|
classes of animals, flatworms and coelentrates. The two layers of
|
|
cells are produced by a process, which I will call planuloid
|
|
development. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">A
|
|
blastula still forms after the cleavage of the egg, but the second
|
|
layer of cells is formed by the inward migration of cells, usually
|
|
from all parts of the surface of the sphere. They clump together at
|
|
the center of the sphere, separating themselves from the outer layer
|
|
of the blastula, and then the outer surface of the inner clump makes
|
|
contact with the outer sphere, or ectoderm. This is the planula. (See
|
|
diagram of Planuloid development) The endoderm is formed by a split
|
|
that starts at the center of the solid clump of cells and continues
|
|
outward in one direction toward the ectoderm, where an opening is
|
|
made for the mouth. The result is a gastrovascular cavity, rather
|
|
than a digestive tract, for there is no second opening. The one
|
|
opening is both mouth and anus. The cavity not only digests food but
|
|
also circulates it to all parts of the body. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; text-indent: -1.91cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><img src="data:image/png;base64,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" name="PlanuloidDev" align="bottom" width="550" height="250" border="0"></font></p>
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|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif">In
|
|
coelentrates, such as the hydra, the gastrovascular sac develops
|
|
long, hollow tentacles around the mouth which are used to paralyze
|
|
prey and pull them into the mouth. But flatworms have a bilateral
|
|
symmetry. The mouth opens from the middle of the body toward the
|
|
ground, and instead of a radial symmetry around it, one of the
|
|
directions becomes the longitudinal axis of the body, and the
|
|
perpendicular direction has a bilateral symmetry. </font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><i><b>Ectolecithal
|
|
development.</b></i> Coelentrates and flatworms, as we mentioned, are
|
|
the simplest kinds of animals. But even their planuloid development
|
|
is too complex to have been a variation on protists. After the solid
|
|
core of cells has formed inside the blastula, and before the inner
|
|
split has opened as a gastrovascular cavity, cilia grow from the
|
|
ectoderm and the planula swims around for a while. But this early,
|
|
pre-sexual stage of its life is surely not the first form that
|
|
animals took, because it has no way of acquiring energy. It is still
|
|
living from the energy reserves of the egg. The clue to the origin of
|
|
multicellular animals can be found in a third kind of development
|
|
which occurs only in certain kinds of flatworms. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; text-indent: -0.64cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
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<font color="#000000"><img 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" name="Ectolecithal" align="bottom" width="576" height="576" border="0"></font></p>
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<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">The
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eggs of these flatworms develop in a medium of energy-rich yolk
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supplied from the outside by nurse cells (ectolecithal development).
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From the cells produced by the cleavage of the egg cell, first, the
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mouth (pharynx) forms. Attached to these cells, another group of
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cells forms a sac to receive what the mouth swallows; they are the
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primitive endoderm, or gut. The ectoderm is formed by a third group
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of cells that constructs an outer layer of cells in the yolk by
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stretching themselves out from the mouth through the yolk around the
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gut. The embryonic mouth then swallows the remaining yolk, which
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|
fills the gut, or gastrovascular cavity.<sup><a class="sdendnoteanc" name="sdendnote2anc" href="#sdendnote2sym"><sup>ii</sup></a></sup>
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|
(See diagram of Ectolecithal development.) </font></font></font>
|
|
</p>
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|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">Ectolecithal
|
|
development is unique. It occurs in just a few species of flatworms,
|
|
but in no other animals. It would be difficult to explain why there
|
|
is such an unusual kind of development unless it is the earliest
|
|
condition. And it suggests how animals may have evolved. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><i><b>The
|
|
origin of ectolecithal development.</b></i> The process of
|
|
ectolecithal development requires only three kinds of cells, each
|
|
with a distinctive kind of behavior. They can all behave at the same
|
|
time, since no movement relative to one another in involved. Thus,
|
|
this random variation would have required only a few cells (maybe as
|
|
few as twelve). An amoeba's cycle of sexual reproduction could well
|
|
have produced that many offspring at once. Assuming that it happened
|
|
on some mechanism for determining its offspring to three different
|
|
kinds of behavior, this lineage could have begun, if each kind of
|
|
cell remained attached to one another and to at least one of the
|
|
other kinds of cell in an asymmetrical way. By synchronizing the
|
|
amoeboid contractions of the mouth cells, the group could trap and
|
|
surround animal-like protists for digestion. The energy supplied by
|
|
their ingested bodies would select a reproductive cycle of this kind,
|
|
if it were possible at all. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">A
|
|
new source of energy is probably the only way that such an unlikely
|
|
process could have been selected. It was probably not to consume
|
|
plants, since a multicellular body is no better suited than
|
|
single-celled animals. Nor is a multicellular body needed to ingest
|
|
prokaryotes. They are on a lower level of biological organization and
|
|
animal-like protists already feed on them. Thus, multicellular
|
|
animals were probably selected in the first place as carnivores,
|
|
which preyed upon larger animal-like protists that, before them, were
|
|
at the top of the food chain. Once the means of constructing
|
|
multicellular bodies had evolved, some variations would, of course,
|
|
eventually evolve ways of using it to acquire energy by ingesting
|
|
plants and prokaryotes. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">This
|
|
origin of animals would account for the ectolecithal development in
|
|
primitive flatworms. It now occurs in eggs, where nurse cells supply
|
|
the yolk, but at first, the offspring may have been constructed in
|
|
the gut using the energy-rich molecules available there, making the
|
|
gastrovascular cavity do double service as a womb. The biological
|
|
behavior guidance system could select the behavior required for
|
|
gestation as an extra stage in the behavior of reproduction by
|
|
turning off the behavior involved in digestion. Amoeboid cells
|
|
already have the capacity to contract and relax depending on the kind
|
|
of object they encounter, and thus, the same cells could play the
|
|
roles of both muscles and neurons in guiding the organism's behavior
|
|
as a whole. Swallowing, for example, could be a contraction generated
|
|
by a signal exchanged among the mouth cells when any member made
|
|
contact with an animal-like protist. It could even have been an
|
|
electromagnetic signal, like neurons, since cells of many kinds are
|
|
responsive to them. Neurons would differentiate as variations of
|
|
ectodermal cells that signalled cells to refrain from feeding in
|
|
hazardous situations, for that would enable them to complete their
|
|
reproductive cycles while others did not. That would explain why
|
|
neurons always differentiate from the ectoderm, never from cells of
|
|
any other kind. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><i><b>Three
|
|
basic kinds of cells.</b></i> This explanation of the origin of
|
|
animals with nervous systems depends on the capacity of offspring of
|
|
a fertilized cell to differentiate into three different kinds of
|
|
cells. The mechanism of differentiation lies in how the egg cell is
|
|
prepared. By leaving different messenger proteins in different parts
|
|
of the cortex or cytoplasm of the egg cell, cleavage gives different
|
|
daughter cells different messenger proteins. The nucleus must enable
|
|
the chromosomes to affect different parts of the cytoplasm in
|
|
different ways, or else it could not set up the process involved in
|
|
reproduction. Thus, the preparation of the egg cell would merely
|
|
elaborate an existing mechanism. The messenger proteins would be keys
|
|
for opening up certain special chromosomes, in addition to those used
|
|
for ordinary housekeeping activities, thereby generating special
|
|
kinds of behavior in them. And assuming the chromosomes are also
|
|
opened up differently at subsequent stages of development, the
|
|
differences would be permanent. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">This
|
|
way of determining the most basic differences among cells, which are
|
|
responsible for the whole process of development, would be an
|
|
elaboration of the protein mechanisms for handling the chromosomes,
|
|
sorting them out, and forming a nucleus that were introduced with the
|
|
evolution of eukaryotes. The mechanism by which sex is determined
|
|
makes it clear that the nucleus handles different chromosomes in
|
|
different ways.<sup><a class="sdendnoteanc" name="sdendnote3anc" href="#sdendnote3sym"><sup>iii</sup></a></sup>
|
|
Since this mechanism is so basic to the operation of the eukaryotic
|
|
cell, evolutionary change would build on it by adding new steps or
|
|
new kinds of behaviors to each of the basic cell kinds at each step.
|
|
Nor could it change easily in the course of evolution.</font></font></font></p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">Only
|
|
three kinds of cells are needed to account for the process of
|
|
development. They would differ from one another in how cells of the
|
|
same kind remain attached to one another and how they relate to the
|
|
other two kinds of cells. Cells that form the ectoderm must attach to
|
|
one another on four sides as the 2-D surface of a sphere while
|
|
orienting themselves to the mouth cells located among them. The inner
|
|
gut cells must also attach to the mouth cells, but they would form
|
|
themselves into a 3-D ball whose outer surface eventually attaches to
|
|
the ectoderm. In addition to attaching to the other two kinds, the
|
|
mouth cells would form an opening in the blastula. Behavior like this
|
|
would require each cell to generate different kinds of behavior
|
|
towards other cells on each side, but that is within the range of
|
|
what eukaryotic cells can do, as the preparation of the egg cell and
|
|
the asymmetrical structures of animal-like protists demonstrate. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">A
|
|
second kind of behavior is also required. Once they are attached to
|
|
one another, the interactions of the different kinds of cells must
|
|
set up the gradients of messenger molecules in which cells at
|
|
different locations can be determined to different kinds of behavior,
|
|
as in multicellular plants. It is not known how these gradients work,
|
|
but we can think about what they must be doing by supposing that a
|
|
gradient involves a pair of messenger proteins with one kind being
|
|
concentrated at one extreme along its direction and the other being
|
|
concentrated at the opposite extreme in that direction; their
|
|
relative strength for any cell would indicate its location. One
|
|
gradient would extend between the mouth cells and the other extreme
|
|
of the blastula (oral and aboral poles). The mouth cells surely have
|
|
a gradient around the opening that they form, which would give the
|
|
blastula a gradient perpendicular to the first. And beside orienting
|
|
themselves in the blastula and picking up its gradients, the
|
|
inner-gut cells must have a gradient of its own that determines the
|
|
center at which the split forms for a digestive cavity. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><i><b>The
|
|
evolution of other forms of development.</b></i> The small scale and
|
|
simple behavior required of such proto-flatworms, together with our
|
|
explanation of the source of energy for development, makes it
|
|
plausible that animals with nervous system originated from an amoeba
|
|
whose offspring after mating included these three different kinds of
|
|
cells. And it is easy to see how planuloid development and
|
|
gastrulation could have evolved from it, thereby suggesting the basic
|
|
evolutionary relationships among animals with nervous systems. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">A
|
|
simple rearrangement of the three kinds of behavior found in the
|
|
primitive, ectolecithal development accounts for planuloid
|
|
development: After cleavage, the ectodermal cells go to work, first,
|
|
constructing the blastula in which the mouth cells have a location
|
|
because of where the division of the egg cell has left them.<sup><a class="sdendnoteanc" name="sdendnote4anc" href="#sdendnote4sym"><sup>iv</sup></a></sup>
|
|
The gradients in the blastula are oriented around the mouth, and once
|
|
the inner gut cells have migrated inward, formed a solid core, and
|
|
made contact with the ectoderm, the split forming in their midst
|
|
could be made to open up toward the mouth's location on the blastula
|
|
by the gradients in the ectoderm. Thus, all the steps in planuloid
|
|
development can be explained as a result of the interactions among
|
|
the three original kinds of cells. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">Gastrulation
|
|
can likewise be explained as a modification of planuloid development
|
|
in which one of the original three kinds of cells drops out of the
|
|
process. Once again, the blastula is the result of the
|
|
ectoderm-forming cells, and mouth-cells have a special location in
|
|
it, establishing its gradients. But instead of cells migrating inward
|
|
to form the inner core of cells, the second layer of cells is formed
|
|
as a result of the behavior of the mouth-cells. That is, invagination
|
|
can be explained as a variation on the behavior that makes an opening
|
|
in the blastula and swallows. It is as if one half of the hemisphere
|
|
swallowed the other half, turning the other half inside out to form a
|
|
second layer of cells beneath the cells of the first half.
|
|
Gastrulation results in a digestive tract with two ends. This could
|
|
also be explained as a elaboration of the behavior of the mouth
|
|
cells. After leading the invagination involved in gastrulation, the
|
|
mouth cells eventually make contact with a special location on the
|
|
blastula and form an opening by interacting with the ectodermal cells
|
|
there. The clump-forming cells that supplied the endoderm for the
|
|
planuloid animal have no role in forming the two layers of cells.</font></font></font></p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">Embryological
|
|
development is our best clue to the branchings of kinds of animals in
|
|
evolution, and the implications of this account of the origin of
|
|
multicellular animals with nervous systems can be made explicit by
|
|
outlining the evolutionary tree to which it leads. We have found that
|
|
the flatworms were the first multicellular animals. The original
|
|
ectolecithal development evolved into the planuloid development of
|
|
flatworms. And coelentrates and gastrulating animals both evolved
|
|
from planuloid flatworms. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">Gastrulating
|
|
animals are of two kinds, proterostomes or deuterostomes, depending
|
|
on the fate of the blastopore, the opening through which the mouth
|
|
cells invaginate. In proterostomes, the blastopore becomes the mouth
|
|
and the second opening becomes the anus, whereas in deuterostomes,
|
|
the blastopore becomes and the anus and the second opening becomes
|
|
the mouth. This is either an early branching among gastrulating
|
|
animals or each evolved independently from the planuloid flatworm.
|
|
And there is a second major difference between them, concerning how
|
|
they form a mesodermal coelom, which suggests the fate of the third
|
|
kind of cell found in the most primitive development that seemed to
|
|
drop out with the evolution of gastrulation. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">A
|
|
mesodermal coelom is a cavity formed within a layer of cells that
|
|
lies between the ectoderm and endoderm. It is the source of internal
|
|
organs, including muscles, gonads, the circulatory system, excretory
|
|
system, and the like. Only the more advanced proterostomes form a
|
|
coelom at all. (Proboscis worms and round worms have no true coelom,
|
|
although they do have a digestive tract.) </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><img 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" name="Mesoderm" align="bottom" width="370" height="432" border="0"></font></p>
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|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif">In
|
|
proterostomes, it is constructed from a special pair of cells which
|
|
were determined by how the cleavage of the egg divides up the egg
|
|
cortex and cytoplasm. As a result of how the blastula is formed and
|
|
gastrulation takes place, these cells wind up near the blastopore,
|
|
which has become the mouth.<sup><a class="sdendnoteanc" name="sdendnote5anc" href="#sdendnote5sym"><sup>v</sup></a></sup>
|
|
After gastrulation is complete and the anus is formed, one cell on
|
|
each side of the blastopore migrates into the area between the
|
|
ectoderm and endoderm, multiplies into a solid mass of cells, and a
|
|
mesodermal coelom is formed by a split that starts in their midst.
|
|
The process is called "schitzocoelous." The mesodermal
|
|
cells are probably descendants of the third kind of cell from the
|
|
primitive, ectolecithal development, which formed a solid clump of
|
|
cells in which a split can develop. With their backs facing either
|
|
the ectoderm or the endoderm, the fronts of these cells face a
|
|
fluid-filled space formed by their splitting, and a 2-D gradient set
|
|
up in it probably determines the cells at different locations to
|
|
become different kinds of organs. The 2-D gradient in the ectoderm
|
|
and endoderm enable them to locate themselves in the body. (See
|
|
diagram of Schitzocoelous.) </font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif">Deuterostomes
|
|
take a different tack, and as we shall see, it makes all the
|
|
difference in their evolutionary destiny. The third kind of cell
|
|
drops out again as gastrulation evolves from planuloid development.
|
|
But the deuterostome forms a mesodermal coelom by enterocoelous, a
|
|
continuation of the behavior of the mouth-cells that accounts for
|
|
gastrulation. That is, after the endoderm invaginates, but before the
|
|
mouth-cells make a second opening in the ectoderm (the animal's
|
|
mouth, in this case), a second invagination takes place, this time
|
|
from the endoderm into the blastocoel, the volume inside the original
|
|
blastula that is now located between the endoderm and ectoderm.<sup><a class="sdendnoteanc" name="sdendnote6anc" href="#sdendnote6sym"><sup>vi</sup></a></sup>
|
|
No cavity is formed by splitting in a solid core; deuterostomes make
|
|
no use of the innerªgut cells from the primitive flatworm
|
|
development. (See diagram of Enterocoelous.)</font></font></p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">If
|
|
this is indeed how animals with nervous systems evolved, then the
|
|
primitive flatworm is their progenitor and all their kinds can be
|
|
classified according to their modifications of its kind of
|
|
embryological development. There are three branches. The simplest
|
|
coelentrates have a larval stage that involves the planula. The other
|
|
coelentrates and ctenophora have evolved from them, although some
|
|
more advanced kinds have evolved a form of gastrulation on their own.
|
|
Thus, these radial animals are one branch. On the second branch are
|
|
proterostomes, and on the third are deuterostomes. Differences in how
|
|
coeloms are formed accompany this defining contrast. As we shall see,
|
|
this difference in embryological development explains the
|
|
surprisingly radical differences between telesensory proterostomes
|
|
and deuterostomes. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><img src="data:image/png;base64,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" name="Relations" align="bottom" width="576" height="690" border="0"></font></p>
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<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><font face="Verdana, sans-serif">T<img src="data:image/png;base64,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" name="TtsOtkCRS04_13" align="right" width="250" height="27" border="0">he
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|
proterostome nervous system development. </font>Neurons always
|
|
develop from the ectoderm. From the beginning, on our speculation,
|
|
the chromosomes containing the genes that transform basic cells into
|
|
neurons are opened up by the protein keys in the ectoderm-forming
|
|
cells. But some additional factor must turn those genes on, since not
|
|
all the cells of the ectoderm become neurons. The mechanism is not
|
|
fully understood, but it apparently depends on gradients in the
|
|
ectoderm. The cells becoming neurons can be evenly distributed over a
|
|
region<sup><a class="sdendnoteanc" name="sdendnote7anc" href="#sdendnote7sym"><sup>vii</sup></a></sup>
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or determined by singularities in the gradient. In the proterostome,
|
|
gradients in the ectoderm (or the effect of special mesodermal cells
|
|
on them) are responsible for cells becoming neurons. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">More
|
|
complex interconnections among neurons in proterostomes are made in
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|
structures, called "ganglia," which are located in various
|
|
places in their bodies and connected by bundles of axons. In each
|
|
ganglion, cell bodies are arranged on the outer surface, and its core
|
|
is a neuropil where the processes synapse with one another. Axons of
|
|
proterostome neurons branch near the cell body. One branch leads into
|
|
the neuropil, and the other branch joins a nerve connecting to other
|
|
ganglia or innervating muscles or sensory receptors at the periphery.
|
|
Ganglia can develop when one or more cells that are determined to
|
|
become neurons at some location multiply and form a cluster. When the
|
|
cluster establishes its own gradient, their locations in it can
|
|
determine neurons to become specific kinds as well as enable them to
|
|
make quite precise connections with one another in each ganglion or
|
|
between them. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">The
|
|
ganglia form in the ectoderm, and they must be interconnected to
|
|
works as an animal behavior guidance system. The gradients of the
|
|
ectoderm are used to connect neurons with one another as well as with
|
|
sensory receptors on the input side and muscle cells on the output
|
|
side. When cells become neurons, they develop processes, dendrites
|
|
and axons, which extend out from the cell body and eventually form
|
|
synapses with certain cells that they encounter. The axons are guided
|
|
to other ganglia, muscles or sensory receptors as they form by
|
|
following the ectodermal (or endodermal) gradients. Neurons at
|
|
different locations in the body are thereby interconnected by nerves.
|
|
</font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">The
|
|
typical structure of the proterostome nervous system is a set of
|
|
ganglia in the ectoderm that are connected with one another and the
|
|
ultimate inputs and outputs throughout the body. That is, the nervous
|
|
system is laid out in the outer skin of the multicellular animal. The
|
|
animal's behavior as a whole depends on the equilibrium reached by
|
|
its entire nervous system, but that equilibrium depends, in turn, on
|
|
the equilibria reached in each of the ganglia as they interact with
|
|
one another by way of the nerves connecting them, given the sensory
|
|
input from the rest of the body. We can see how the basic structure
|
|
of the proterostome nervous system follows the gradients of the
|
|
ectoderm by looking at the nervous systems of simpler animals, those
|
|
with a planuloid development, because the gradients in the
|
|
proterostome are simply how gastrulation has modified them. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">The
|
|
bodies and nervous systems of flatworms and coelentrates form from a
|
|
larval stage called the planula, which as we have seen, is produced
|
|
by the interaction of the three basic kinds of cells. The ectodermal
|
|
gradients depend on the location of the mouth cells, and when the
|
|
inner core of cells joins the ectoderm, it picks up the ectodermal
|
|
gradients, enabling the split that forms in their midst to open up in
|
|
the direction of the mouth. The mouth is the only opening, and body
|
|
is a sac formed of two-layers of cells. There is a gradient between
|
|
its oral and aboral poles and another gradient running around the
|
|
body perpendicular to it. (See diagram of The planula.)</font></font></font></p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><img src="data:image/png;base64,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" name="Planula" align="bottom" width="479" height="429" border="0"></font></p>
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<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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<font color="#000000"><font face="Times New Roman, serif">The body of
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the hydra, for example, is complete, once tentacles form around the
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mouth as elongated extensions of this gastrovascular cavity. Its
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nervous system is just a network of neurons differentiated at random
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in the gradients of its sac-like body, with a slightly higher
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concentration around the mouth. They are responsible for reflexes
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involving longitudinal muscles at the base of ectodermal cells and
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latitudinal muscles at the base of endodermal cells by which hydra's
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tentacles wrap around prey that swim by and pull their paralyzed
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bodies into its mouth. There is a second and maybe a third network of
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neurons which enable hydra to throw its tentacles out in various
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directions seeking prey and to somersault to more favorable
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situations by attaching its tentacles to the ground and throwing its
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body over them. But it lacks extroªsensory organs (like all
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coelentrates), getting by with somatosensory input and phototropisms.
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</font></font>
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</p>
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|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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<font color="#000000"><font face="Times New Roman, serif">The
|
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flatworm has essentially the same structure as the hydra, except that
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one of the gradients that is perpendicular to the oral-aboral axis is
|
|
a longitudinal gradient for the body. That is, it has a bilateral
|
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body with its mouth located near the middle of its ventral side. The
|
|
bilateral body enables it to move about in space head first, and the
|
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head has primitive telesensory organs to guide it: Pigmented eye
|
|
spots detect the direction of light and the motion of object and
|
|
lobes on the sides of its head with mechanoreceptors and
|
|
chemoreceptors detect the direction of water flow and detect certain
|
|
kinds of molecules in it. Like the hydra, the flatworm has a nerve
|
|
net throughout its body which coordinates the body with the pharynx
|
|
as it feeds, but superimposed on it is a second nervous system, which
|
|
is organized like a ladder along the length of the dorsal side of its
|
|
body. At least two, and sometime four, six or eight nerve chords run
|
|
in parallel from head to tail, with regular latitudinal nerves
|
|
connecting them and innervating the muscles of the body. At the head,
|
|
there are ganglia where neurons from the sensory receptors intersect
|
|
with the longitudinal nerves, which trigger or repress the reflexes
|
|
by which it moves. Both nervous systems are laid out in the gradients
|
|
of its simple body. The nerve net centered around the mouth generates
|
|
feeding behavior, whereas the longitudinal, ladder-type nerves
|
|
centered at the head generates locomotion. The balance between them
|
|
presumably selects the kind of behavior. (See diagram of Flatworm.) </font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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|
<font color="#000000"><img src="data:image/png;base64,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" name="Flatworm" align="bottom" width="433" height="267" border="0"></font></p>
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<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">The
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basic structure of the proterostome nervous system can be seen as a
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transformation of the flatworm nervous system that result from the
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evolution of gastrulation from the flatworm's planuloid development.
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On our speculation, the second layer of cells is formed by the
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"mouth-cells," which are located at the oral extreme of the
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oral-aboral gradient in the blastula. The mouth-cells lead the
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invagination of one hemisphere of the blastula that forms a second
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layer of cells, but they do not stop there. The invaginating endoderm
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does not seek out the aboral pole of the blastula to locate the anus;
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instead, it seeks out the tail in the longitudinal gradient of the
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ectoderm. The blastopore, which becomes the mouth, is also shifted
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from the middle of the ventral side toward the head, shortening the
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ventral side anterior to the mouth. Thus, the original oral-aboral
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gradient in the endoderm coincides posterior to the mouth with the
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longitudinal gradient of the ectoderm. This produces a new framework
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of gradients in which the nervous system is laid out. The result is a
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nervous system composed of a pair of nerve chords running along the
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ventral side of the body with one pair of ganglia connecting them
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anterior to the mouth and at least another pair of ganglia posterior
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to the mouth. (See diagram of Proboscis worm.)</font></font></font></p>
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<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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<font color="#000000"><img 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" name="Proboscis" align="bottom" width="410" height="225" border="0"></font></p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">If
|
|
this is how to understand the evolution of gastrulation form the
|
|
planuloid development of flatworms, we can see how proterostomes are
|
|
trapped into a nervous system with two pairs of ganglia encircling
|
|
the mouth. One pair is anterior to the mouth, the other pair
|
|
posterior, and connections between them encircle the mouth.
|
|
Reproductive causation has never extricated the nervous system from
|
|
the mouth in any proterostome. As our speculation suggests, the
|
|
reason is that the biological behavior guidance system uses gradients
|
|
in the ectoderm to determine cells as neurons and gastrulation has
|
|
organized those gradients around the mouth. With bilateral bodies,
|
|
nerves apparently cannot be differentiated along the length of the
|
|
body except symmetrically, in pairs. Although the parallel nerves are
|
|
sometimes fused through most of the body of higher proterostomes, at
|
|
the head, they still lie on either side of the mouth and are
|
|
reconnected anterior to it.<sup><a class="sdendnoteanc" name="sdendnote8anc" href="#sdendnote8sym"><sup>viii</sup></a></sup></font></font></font></p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif">This
|
|
structure is clearest in the simplest proterostomes, proboscis worms
|
|
(Nemertina) and round worms (Aschelminthes). In higher proterostomes,
|
|
such as mollusks (clams and squid), annelids (segmented worms), and
|
|
arthropods (crustaceans, spiders and insects), the mesodermal coelom
|
|
gives the body a more complex structure. The mesodermal coelom
|
|
superimposes a structure on the gradients of the ectoderm and
|
|
endoderm, which may modify the structure of the nervous system, but
|
|
it does not enable the nervous system to avoid having two pairs of
|
|
ganglia encircling the mouth.</font></font></p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif">The most
|
|
radical effect of the mesodermal coelom is the segmentation found in
|
|
annelids and arthropods. It results from a special kind of division
|
|
of the mesodermal cells. After migrating into the space between
|
|
ectoderm and endoderm, they divide into many pairs of stem cells.
|
|
Each pair marks off a segment in the ectoderm, and after forming a
|
|
solid mass of cells, each clump splits and forms a coelom with a
|
|
complement of organs. Each segment is roughly equivalent to a
|
|
gastrula, and the series is chained together, mouth to anus, as a
|
|
continuous digestive tract. The segmentation they impose on the
|
|
gradient in the ectoderm affects the structure of the nervous system.
|
|
In most segments, there are only two main ganglia, which are
|
|
connected along the ventral side by a pair of (fused) nerves, as if
|
|
the pair of ganglia anterior to the mouth in each segment were
|
|
suppressed. But at the head, the anterior segment, where the nervous
|
|
system is centralized, there are still two pair of ganglia encircling
|
|
the mouth, with the telesensory organs supplying input to the
|
|
anterior pair. Thus, segmentation does not enable proterostomes to
|
|
escape the trap of having at least two pairs of ganglia encircling
|
|
the mouth. A far more radical change is needed to escape the
|
|
ectodermal gradients left by gastrulation.</font></font></p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><font face="Verdana, sans-serif">T<img src="data:image/png;base64,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" name="TtsOtkCRS04_14" align="right" width="250" height="23" border="0">he
|
|
deuterostome nervous system development. </font>Deuterostome
|
|
development makes it possible to lay out a centralized nervous system
|
|
without encircling the mouth. Neurons still differentiate from the
|
|
ectoderm, but the ectoderm from which they differentiate is a region
|
|
that has separated from the outer skin and rolled itself up as a
|
|
neural tube which is contained as a unit inside the body. The
|
|
structure of the nervous system can be laid out free of the gradients
|
|
of the gastrula because the neural tube uses gradients of its own to
|
|
determine neurons to different kinds and connect them with one
|
|
another. Since the deuterostome's embryological development is what
|
|
makes this possible, that is where we begin. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><i><b>Deuterostome
|
|
development.</b></i> Like proterostomes, deuterostomes develop by
|
|
gastrulation, rather than by forming a planula. After cleavage, the
|
|
daughter cells arrange themselves as the surface of a fluid-filled
|
|
sphere, called the blastula. A second layer of cells is formed as one
|
|
hemisphere invaginates and lines itself up along the underside of the
|
|
remaining spherical surface. The outer layer of cells is the
|
|
ectoderm; the inner layer of cells is the endoderm; and the hole
|
|
through which cells have invaginated is the blastopore. Deuterostome
|
|
development differs from proterostome development because the
|
|
blastopore becomes the anus and the second opening becomes the mouth
|
|
-- which is just the opposite of proterostome development. The animal
|
|
has a longitudinal axis running from mouth to anus, and properly
|
|
speaking, the endoderm marks the boundary between body and world no
|
|
less than the ectoderm, for it becomes the digestive tract (and
|
|
respiratory system in higher chordates) by which the body interacts
|
|
with other objects in space, albeit under conditions that are more
|
|
easily controlled. (See diagram of Gastrulation in amphiouxus.) </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; text-indent: -2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
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<font color="#000000"><img 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" name="Gastru2" align="bottom" width="576" height="289" border="0"></font></p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">The
|
|
body's internal structure depends on the next step in the process,
|
|
which is also differs radically from the proterostome. Its task is a
|
|
twofold. On the one hand, it forms a third layer of cells, or
|
|
mesoderm, between the ectoderm and endoderm, and on the other, it
|
|
forms a neural tube just beneath the surface of the dorsal ectoderm.
|
|
The third layer of cells includes not only the coelom, from which
|
|
muscles, a circulatory system and various other organs develop, but
|
|
also the notochord, which is the precursor of the spine. There is a
|
|
symmetry abut these two developments because at the end of
|
|
gastrulation, the segment of endoderm from which the chordamesoderm
|
|
develops lies just beneath the neural plate, the section of ectoderm
|
|
from which the neural tube forms. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif">The
|
|
notochord and mesoderm are formed by enterocoelous, a process of
|
|
out-pouching by the endoderm into the space between the endoderm and
|
|
ectoderm, which was originally the blastocoel. The cells involved are
|
|
the "mouth-cells" that led the process of gastrulation by
|
|
invading the blastocoel in the first place, and thus, enterocoelous
|
|
is just a continuation of the cell movements that took place in
|
|
gastrulation. Gastrulation first began on the dorsal side of the
|
|
blastula, and a section of endoderm that runs the whole length of the
|
|
gastrula along the dorsal side is involved in the out-pouching. This
|
|
surface of the endoderm bends in toward the adjacent ectoderm,
|
|
forming two sections of cells, both of which break off from the
|
|
endoderm, allowing the rest of the endoderm to close behind it,
|
|
thereby restoring the surface of the archenteron. The out-pouching
|
|
cells become the mesodermal coelom on one side of the body, and a
|
|
notochord forms where they meet along the midline. In fact, these
|
|
out-pouchings become a series of segments, for they are divided into
|
|
segments, like the notochord, which run the length of the body. They
|
|
eventually spread out to form a complete layer of cells between the
|
|
ectoderm and the remaining endoderm around the sides and along
|
|
ventral side of the body. </font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif">The nervous
|
|
system is formed by a similar out-pouching, but this time from the
|
|
ectoderm. The cells involved are a section of ectoderm, the neural
|
|
plate, that runs the length of the dorsal side of the gastrula just
|
|
above the medial chordamesoderm. The neural plate separates from the
|
|
ectoderm and sinks beneath the ectoderm. As the ectoderm closes
|
|
behind it, restoring the outer skin of the body, the neural plate
|
|
rolls itself up into a tube in the space between the ectoderm and
|
|
chordomesoderm along the entire length of the body.<sup><a class="sdendnoteanc" name="sdendnote9anc" href="#sdendnote9sym"><sup>ix</sup></a></sup>
|
|
(See diagram of Neurulation in amphiouxus.) </font></font>
|
|
</p>
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<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; text-indent: -0.64cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
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" name="Neurulation" align="bottom" width="575" height="215" border="0"></font></p>
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|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif">Ectodermal
|
|
cells are determined to become part of the neural plate by the effect
|
|
of the choradmesoderm on them during the process of gastrulation. And
|
|
both the neural plate and chordamesoderm are segmented longitudinally
|
|
in the process. That is, by the time the gastrula is formed, cells in
|
|
different segments along the length of either structure have already
|
|
been determined to become different kinds of cells. How this is
|
|
accomplished is not known, but conceivably segmentation is induced by
|
|
a pulse occurring during gastrulation that marks cells at regular
|
|
intervals along its length as they invaginate. In any case,
|
|
segmentation is a product of gastrulation, the process by which the
|
|
"mouth-cells" form a second layer of cells in
|
|
deuterostomes, not an effect of the special inner-gut cells from the
|
|
primitive ectolecithal development, as in proterostomes. What is
|
|
more, not only are cells located in different segments of the neural
|
|
tube and mesodermal coeloms already different, but each segment has a
|
|
2-D gradient of its own in which cells can be differentiated. </font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
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<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">T<img 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" name="Amphioxus" align="right" width="278" height="267" border="0">he
|
|
basic structure of the body at this stage is a set of tubes with the
|
|
blastopore at one end and a mouth formed at the other. The outer tube
|
|
is the ectoderm, and the innermost concentric tube is the endoderm.
|
|
Filling the volume between them are several more tube-like
|
|
structures: On the dorsal side is the hollow neural tube and just
|
|
beneath it is the notochord. On each side of them lies a tube divided
|
|
into a series of hollow areas, the coeloms. (See diagram of
|
|
Crosssection of embryo of amphioxus.) </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif">Although
|
|
the segmented neural tube is the kind of basic structure that
|
|
deuterostome development makes possible in the nervous system, it is
|
|
of little use in the decentralized nervous systems at the
|
|
somatosensory stage. There is a somatosensory deuterostome with a
|
|
segmented neural tube, namely, Amphioxus, a cephalochordate. The sea
|
|
squirt (a tunicate classified as an urochordate) also has a segmented
|
|
neural tube at the larval stage. Even the rather primitive acorn worm
|
|
(a hemichordate) has a neural tube, although it is not segmented.<sup><a class="sdendnoteanc" name="sdendnote10anc" href="#sdendnote10sym"><sup>x</sup></a></sup>
|
|
However, the neural tube is not a universal feature of deuterostomes.
|
|
It is not found in echinoderms, such as the sea star. The sea star
|
|
has a solid nerve ring to control the tube feet in each arm, and,
|
|
like acorn worms, there is also a nerve plexus lying underneath the
|
|
ectoderm over the entire body. The nerve plexus is an apparently
|
|
haphazard network of neurons, and the neural tube seems to be just a
|
|
section of such a plexus that has been rolled up into a tube during
|
|
development in most kinds of deuterostomes, including all telesensory
|
|
deuterostomes.<sup><a class="sdendnoteanc" name="sdendnote11anc" href="#sdendnote11sym"><sup>xi</sup></a></sup>
|
|
</font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><i><b>Independence
|
|
of the nervous system.</b></i> The most obvious advantage of
|
|
separating the ectoderm from which the nervous system will develop
|
|
from the outer skin is that it extricates the nervous system from the
|
|
convoluted gradients of the ectoderm, which leaves proterostomes with
|
|
two pair of ganglia surrounding the mouth. In the same way, it
|
|
probably also enables reproductive causation to shape the body and
|
|
its organs in whatever way that is useful in generating behavior
|
|
without disrupting the nervous system, as it surely does in
|
|
proterostomes with its ganglia and nerves running throughout the
|
|
body. It also enables the nervous system to be divided into segments
|
|
without the complete divisions of the body found in segmented
|
|
proterostomes, since the segments are imprinted on chordamesoderm and
|
|
neural tube by gastrulation, not by special mesodermal cells. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif">The unity
|
|
that the neural tube gives the nervous system by contrast to the
|
|
proterostome might well be compared to the contrast between the
|
|
eukaryote and prokaryote behavior guidance systems. The prokaryote
|
|
has a single loop of DNA attached to its cell wall, and the
|
|
protein-DNA interaction that selects the kind of behavior occurs in
|
|
the same space as the protein interactions that generate its
|
|
behavior. In eukaryotes, DNA-protein interactions like those that
|
|
guide prokaryotic behavior are contained within a nucleus, separate
|
|
from the rest of the cell. Since its behavior is selected by an
|
|
equilibrium involving an interaction of proteins and multiple
|
|
chromosomes that is protected from interference by processes in the
|
|
cytoplasm, eukaryotes can generate behavior on a higher scale than
|
|
prokaryotes. Although the chordate is not on a higher level of
|
|
natural organization from proterostomes, the neural tube, like the
|
|
nucleus, does give the chordate nervous system a unity within the
|
|
body that also enables it to generate behavior on an entirely new
|
|
scale. Not only is the chordate nervous system not entangled with the
|
|
organs generating the animal's behavior, but also when it is
|
|
centralized at the second stages of zoological evolution, the
|
|
processing required to select appropriate goals for the object and
|
|
adjust its behavior to its spatial location can be carried out
|
|
without interference by the rest of the body. </font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">By
|
|
separating the ectoderm which can differentiate into neurons from the
|
|
rest of the body, the chordate has an additional step in setting up
|
|
its nervous system: It must connect the nervous system to the sensory
|
|
receptors and muscles in various parts of the body. The proterostome
|
|
was spared this task by determining cells as neurons near the
|
|
locations in the body where they would make their connections. But
|
|
given the gradients that are established by gastrulation, it is a
|
|
relatively simple task. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif">Although in
|
|
Amphioxus, the connections between the neural tube and the body are
|
|
made by processes from the neurons located in the neural tube, in the
|
|
higher chordates, sensory cells (and neurons serving the viscera)
|
|
derive from the neural crest. The neural crest is a group of cells
|
|
that breaks away from the edge of the neural plate before it forms
|
|
into a tube and individual cells migrate to locations in the body. In
|
|
either case, the neurons that connect the neural tube with the body
|
|
can easily find their targets. Not only does the ectoderm as a whole
|
|
have a 2-D gradient of messenger molecules, but segments are also
|
|
marked off in it by the segmentation of the mesodermal coelom. Given
|
|
how segments are imprinted, mesodermal segments surely correspond to
|
|
segments of the neural tube (and neural crest), enabling the same
|
|
gradient mechanisms to be used in making connections at both ends.
|
|
Neurons may even use the 2-D gradients set up within each mesodermal
|
|
segment to locate the precise muscle or gland cells to which they
|
|
will connect or to distribute their connections with internal organs
|
|
evenly. </font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt"><i><b>Neurons
|
|
born in 2-D arrays.</b></i> The advantages that a neural tube affords
|
|
a centralized nervous system have been described negatively, as
|
|
overcoming the deficiencies in proterostome nervous systems that
|
|
derive from using the ectodermal gradients to lay out its structure.
|
|
But positive advantages are what make higher levels of neurological
|
|
organization possible. The 2-D gradient in which neurons can be
|
|
determined to special kinds and make connections with one another are
|
|
supplied by the neural tube. That is, since neurons are born with
|
|
labels indicating their segment and 2-D location within that segment,
|
|
there is no need for neurons to multiply and set up their own
|
|
gradient to become neurons of specific kinds, as ganglia do. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">Each
|
|
gradient, we have assumed, involves a pair of messenger proteins,
|
|
with one being concentrated at one extreme along its direction and
|
|
the other being concentrated at the opposite extreme. The location of
|
|
any cell in any gradient is indicated by their relative strength, and
|
|
thus, the location of a cell in the neural tube is indicated by its
|
|
location in two gradients: one in the longitudinal direction, and one
|
|
that extends from the ventral midline of the neural tube to the
|
|
dorsal midline where the two sides of the neural plate closed.
|
|
Indeed, there are two sets of these 2-D gradients in the neural tube,
|
|
since each half of the bilateral body would be a mirror image of the
|
|
other. The third gradient, extending from the central canal of the
|
|
neural tube to its outer border, is used to guide neurons in
|
|
migrating and making connections, but not to determine neurons to
|
|
specific kinds. Furthermore, since the neural tube is divided into
|
|
segments along its length, the cells in each segment are different
|
|
from those in other segments. And with each segment having its own
|
|
2-D gradient, it is easy to see how complex interconnections can be
|
|
set up. </font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 2.54cm; margin-right: 1.27cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">Suppose
|
|
that once the gradients are established in each segment, each cell
|
|
somehow records the relative strength of each pair of messenger
|
|
proteins in which it finds itself. Some cells that are differentiated
|
|
throughout the neural tube remain there; as they elongate, labels
|
|
from the original gradient are posted, and these processes enable
|
|
other cells to find their way about. They are called "glial"
|
|
cells. At an earlier stage of development, cells of the neural tube
|
|
are determined to become neurons. Neurons always divide at the inner
|
|
surface of the neural tube bordering on the central canal.<sup><a class="sdendnoteanc" name="sdendnote12anc" href="#sdendnote12sym"><sup>xii</sup></a></sup>
|
|
When they send processes or migrate to other locations, they can
|
|
easily line themselves up in a 2-D array with other cells from the
|
|
same segment, because they can use the labels from their original
|
|
locations in the neural tube to seek out the place where the balance
|
|
between the messenger proteins of cells on one side is greater and on
|
|
the opposite side less than their own. Or when processes arrive at
|
|
another segment, they can superimpose themselves in a regular way on
|
|
the cells already located there by seeking out their own location in
|
|
the gradients of local cells. In short, entire 2-D arrays of neurons
|
|
from one segment of the neural tube can be connected with 2-D arrays
|
|
of neurons in other segments in a regular, topographical way. Indeed,
|
|
that is what every neuron from a segment would do, unless they were
|
|
differentiated from one another.<sup><a class="sdendnoteanc" name="sdendnote13anc" href="#sdendnote13sym"><sup>xiii</sup></a></sup>
|
|
</font></font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif">Vision is a
|
|
good example of the advantage of the 2-D arrays built into the
|
|
gradients of the neural tube. The retina of the eye derives in
|
|
development from a section of the neural tube that migrates as a
|
|
whole to the ectoderm and determines cells located there to become a
|
|
lens and an eyeball surrounding it. The neural tube's gradients
|
|
supply each neuron in the retina with information about its location
|
|
in a two-dimensional matrix. Thus, their axons are able to keep their
|
|
order as they project back to the neural tube. The optic nerve is a
|
|
single cable, often containing millions of axons, and labels from
|
|
their built-in gradients enable them to keep line up, even when the
|
|
two optic nerves merge and the axons from half of each retina are
|
|
sent off in a different direction. And they can easily superimpose
|
|
themselves in an orderly way on 2-D arrays of neurons from other
|
|
segments, which are their targets. </font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif">The
|
|
contrast to the proterostome nervous system could not be starker.
|
|
Cephalopods, such as squid and octopus, have camera-type eyes which
|
|
are the equal of vertebrates, but their nervous systems is a
|
|
collection of ganglia that are arranged around the mouth. The eyes
|
|
feed sensory input to the optic lobes, which connect with other
|
|
lobes, and behavior is guided by the equilibrium reached by an
|
|
interaction that depends on the equilibria reached in each of various
|
|
lobes. Visual input is conveyed by the configuration of firings in
|
|
2-D arrays of neurons, but in order to operate a camera-type eye,
|
|
cephalopods must build up complex 2-D arrays of neurons within
|
|
special ganglia in order to carry the information. A glance at the
|
|
basket-weave of the optic nerve in the octopus makes it clear that a
|
|
good part of the biological behavior guidance system's machinery for
|
|
differentiating cells is used up simply keeping them straight as they
|
|
project to the target. That is, a kind of structure that is very near
|
|
the limit of what the proterostome development can accomplish is
|
|
supplied by deuterostome development at the outset as the foundation
|
|
on which further structure is constructed. </font></font>
|
|
</p>
|
|
<p lang="en-US" class="western" align="left" style="margin-left: 3.81cm; margin-right: 2.03cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
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" name="Octopus" align="bottom" width="384" height="384" border="0"></font></p>
|
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<p lang="en-US" class="western" align="left" style="margin-left: 1.27cm; margin-right: 2.54cm; margin-top: 0.49cm; margin-bottom: 0.49cm; line-height: 100%; widows: 0; orphans: 0">
|
|
<font color="#000000"><font face="Times New Roman, serif"><font size="3" style="font-size: 12pt">Although
|
|
the somatosensory nervous system gets by with single neurons serving
|
|
the functions of registering input, generating output and selecting
|
|
between kinds of behavior, the telesensory nervous system requires at
|
|
least one 2-D array of cells for vision and a centralized system to
|
|
make use of it. Proterostomes and the chordates among deuterostomes
|
|
are both capable of these two levels of natural organization in the
|
|
nervous system. As I have mentioned, however, the third animal stage
|
|
of evolution requires complete circuits of such 2-D arrays which can
|
|
interact with one another as units to register input and generate
|
|
output. The fourth animal stage involves the interaction between
|
|
various channels through both input and output circuit of 2-D arrays.
|
|
The machinery required to connect 2-D arrays of cells from ganglia is
|
|
so complex that it is not possible for these mechanism to evolve as
|
|
variations on the proterostome nervous system. But deuterostome
|
|
development makes possible a neural tube that supplies labels to
|
|
cells by which entire 2-D arrays of neurons are connected with
|
|
relative ease. In chordates, therefore, a third level of neurological
|
|
organization can occur as a variation on the second level, and a
|
|
fourth level can occur as a variation on the third level. Given the
|
|
possibility of higher levels of neurological organization,
|
|
reproductive causation inevitably makes them actual. Thus, our
|
|
interpretation of embryology gives us an explanation why a third and
|
|
fourth stage of zoological evolution occurs in deuterostomes, but not
|
|
in any proterostome.</font></font></font></p>
|
|
<div id="sdendnote1">
|
|
<p lang="en-US" class="sdendnote-western" style="margin-top: 0cm; margin-bottom: 0.25cm">
|
|
<a class="sdendnotesym" name="sdendnote1sym" href="#sdendnote1anc">i</a>
|
|
This occurs in two different ways, marking the most basic difference
|
|
between kinds of complex animals. In one case, the blastopore
|
|
becomes the mouth and the second opening becomes the anus. In the
|
|
other, the blastopore becomes the anus and the second opening
|
|
becomes the mouth. The former animals are called proterostomes,
|
|
whereas the latter are called deuterostomes. This is a significant
|
|
difference that will occupy us later, for only in deuterostomes do
|
|
stages of zoological evolution lead all the way to reason.</p>
|
|
</div>
|
|
<div id="sdendnote2">
|
|
<p lang="en-US" class="sdendnote-western" style="margin-top: 0cm; margin-bottom: 0.25cm">
|
|
<a class="sdendnotesym" name="sdendnote2sym" href="#sdendnote2anc">ii</a>
|
|
The embryonic mouth then disappears and reappears later. See Earl D.
|
|
Hanson, ”The Origin and Early Evolution of Animals• (London,
|
|
Wesleyan University Press, 1977), pp. 511-513. Also R. J. Skaer,
|
|
"Planarians," in G. Reverberi, (ed.), ”Experimental
|
|
Embryology of Marine and Fresh-Water Invertebrates•, (Amsterdam,
|
|
North-Holland Publishing Company, 1971), pp. 104-125</p>
|
|
</div>
|
|
<div id="sdendnote3">
|
|
<p lang="en-US" class="sdendnote-western" style="margin-top: 0cm; margin-bottom: 0.25cm">
|
|
<a class="sdendnotesym" name="sdendnote3sym" href="#sdendnote3anc">iii</a>
|
|
In most higher animals, one kind of chromosome has two fundamentally
|
|
different forms, called X and Y. Females have two X chromosomes,
|
|
whereas males have both an X and a Y chromosome. However, only one
|
|
of the X chromosomes is opened up in the female; the other X
|
|
chromosome is wrapped up and set aside as a unit called the "Barr
|
|
body." Both X and Y chromosomes are opened up in the male, and
|
|
there is no Barr body.</p>
|
|
</div>
|
|
<div id="sdendnote4">
|
|
<p lang="en-US" class="sdendnote-western" style="margin-top: 0cm; margin-bottom: 0.25cm">
|
|
<a class="sdendnotesym" name="sdendnote4sym" href="#sdendnote4anc">iv</a>
|
|
The division of the egg cell, or cleavage, is highly indeterminate
|
|
in the most primitive, ectolecithal flatworm egg, but it occurs in a
|
|
regular way in flatworms with planuloid development and in all
|
|
higher animals. It is likely that determinate cleavage ensures that
|
|
cells with certain parts of the egg cortex or cytoplasm end up with
|
|
the right location on the blastula in order for their behavior
|
|
toward one another to construct the animal. The planuloid flatworms
|
|
have either a duet-type spiral cleavage or the quartet-type spiral
|
|
cleavage found in proterostomes. But deuterostomes have a radial
|
|
cleavage, presumably because their kind of gastrulation and way of
|
|
forming a mesodermal coelom is so different.</p>
|
|
</div>
|
|
<div id="sdendnote5">
|
|
<p lang="en-US" class="sdendnote-western" style="margin-top: 0cm; margin-bottom: 0.25cm">
|
|
<a class="sdendnotesym" name="sdendnote5sym" href="#sdendnote5anc">v</a>
|
|
The passing down of a portion of the egg cortex or cytoplasm to the
|
|
right place in the blastula can be seen in the cleavage of certain
|
|
mollusks; it is a "polar lobe" that is formed before each
|
|
division that ensures that it is bestowed on the right daughter cell
|
|
and thereby winds up in the right place on the blastula. In insects,
|
|
the process of development is greatly modified. Instead of a regular
|
|
process of cleavage, the blastula is formed directly from the egg
|
|
cortex by the migration of copies of the egg nucleus to locations on
|
|
its plasma membrane, where each nucleus separates itself by setting
|
|
up a plasma membrane. But the effect is the same, since the
|
|
mesodermal coelom still derives (by the splitting of a solid mass of
|
|
cells) from a pair of cells that inherit a certain part of the egg
|
|
cortex.</p>
|
|
</div>
|
|
<div id="sdendnote6">
|
|
<p lang="en-US" class="sdendnote-western" style="margin-top: 0cm; margin-bottom: 0.25cm">
|
|
<a class="sdendnotesym" name="sdendnote6sym" href="#sdendnote6anc">vi</a>
|
|
In the sea star and other echinoderms, the mesodermal coeloms are
|
|
spheres that pinch off from the endoderm in the blastocoel before
|
|
the mouth is formed. But in chordates, it is a more refined process
|
|
which also includes a similar out©pouching into the blastocoel from
|
|
the ectoderm.</p>
|
|
</div>
|
|
<div id="sdendnote7">
|
|
<p lang="en-US" class="sdendnote-western" style="margin-top: 0cm; margin-bottom: 0.25cm">
|
|
<a class="sdendnotesym" name="sdendnote7sym" href="#sdendnote7anc">vii</a>
|
|
Cells of a specific kind can be distributed evenly over a region by
|
|
a simple device. As cells in the region all face some condition that
|
|
tends to open up the special genes, the cell to do it first sends
|
|
out a protein that signals its neighbors to refrain. Thus, a
|
|
scattering of cells at different locations are determined.</p>
|
|
</div>
|
|
<div id="sdendnote8">
|
|
<p lang="en-US" class="sdendnote-western" style="margin-top: 0cm; margin-bottom: 0.25cm">
|
|
<a class="sdendnotesym" name="sdendnote8sym" href="#sdendnote8anc">viii</a>
|
|
It might seem that parallel nerves could be fused along the whole
|
|
length of the body if they ran on the dorsal, rather than ventral
|
|
side, where the mouth is. But that would not integrate the
|
|
longitudinal nerves, which use telesensory organs to guide
|
|
locomotion, with the nerve net around the mouth, which generates the
|
|
feeding behavior. Thus, a ventral location was probably locked in
|
|
with the evolution of gastrulation, and neither the anterior nor the
|
|
posterior ganglia could be dropped since the mouth was originally
|
|
located in the middle of the longitudinal gradient.</p>
|
|
</div>
|
|
<div id="sdendnote9">
|
|
<p lang="en-US" class="sdendnote-western" style="margin-top: 0cm; margin-bottom: 0.25cm">
|
|
<a class="sdendnotesym" name="sdendnote9sym" href="#sdendnote9anc">ix</a>
|
|
In higher chordates, cells at the edge of the neural plate, called
|
|
the neural crest, break off before the neural tube is complete and
|
|
become sensory neurons or neurons serving the viscera. â In most of
|
|
the body, the neural tube encloses a canal (the central canal of the
|
|
spinal chord). But toward the end opposite the blastopore, where the
|
|
mouth eventually forms, the neural tube swells slightly, the two
|
|
sides of the neural plate do not close as a tube, and they are
|
|
separated by ventricles. This is where the brain forms in
|
|
vertebrates. The somatosensory chordate, Amphioxus, has no brain and
|
|
the central canal remains open to the outside.</p>
|
|
</div>
|
|
<div id="sdendnote10">
|
|
<p lang="en-US" class="sdendnote-western" style="margin-top: 0cm; margin-bottom: 0.25cm">
|
|
<a class="sdendnotesym" name="sdendnote10sym" href="#sdendnote10anc">x</a>
|
|
The acorn worm (Enteropneusta) is a large, worm that burrows in the
|
|
sand. Although it lacks a notochord, which accompanies the formation
|
|
of the neural tube in all other cases, which are segmented, it has
|
|
neural tube dorsal to its mouth followed by a solid nerve chord that
|
|
runs through the remainder of the body. And lying just beneath the
|
|
ectoderm over most of its body is a plexus of neurons. But the
|
|
neural tube is the center of its behavior guidance system: It
|
|
selects the kind of behavior for each situation, insofar as it has
|
|
whole-body behavior at all.</p>
|
|
</div>
|
|
<div id="sdendnote11">
|
|
<p lang="en-US" class="sdendnote-western" style="margin-top: 0cm; margin-bottom: 0.25cm">
|
|
<a class="sdendnotesym" name="sdendnote11sym" href="#sdendnote11anc">xi</a>
|
|
As noted, one minor exception is the tiny arrow worm, chaetognatha.</p>
|
|
</div>
|
|
<div id="sdendnote12">
|
|
<p lang="en-US" class="sdendnote-western" style="margin-top: 0cm; margin-bottom: 0.25cm">
|
|
<a class="sdendnotesym" name="sdendnote12sym" href="#sdendnote12anc">xii</a>
|
|
There are two exceptions in human brains, including the cells from
|
|
which the striatum and amygdala (the basal ganglia) in the forebrain
|
|
form and certain cells in the cerebellum.</p>
|
|
</div>
|
|
<div id="sdendnote13">
|
|
<p lang="en-US" class="sdendnote-western" style="margin-top: 0cm; margin-bottom: 0.25cm">
|
|
<a class="sdendnotesym" name="sdendnote13sym" href="#sdendnote13anc">xiii</a>
|
|
When neurons are determined by the neurons with which they synapse
|
|
after having migrated or constructed processes, the way of
|
|
determining the cells is to allow those that do not make synapses
|
|
die. Thus, the development of the brain involves the weeding out of
|
|
cells after they have tried to make connections as well as
|
|
determining them before they begin.</p>
|
|
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|
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